Nasonex is a drug with the active ingredient of mometasone furoate monohydrate and was created by the Schering Corporation.
Results Of Interest:
When administered to pregnant mice, rats, and rabbits, mometasone furoate increased fetal malformations. The doses that produced malformations also decreased fetal growth, as measured by lower fetal weights and/or delayed ossification. Mometasone furoate also caused dystocia and related complications when administered to rats during the end of pregnancy.
In rabbits, mometasone furoate caused multiple malformations (eg, flexed front paws, gallbladder agenesis, umbilical hernia, hydrocephaly)
Controlled clinical studies have shown intranasal corticosteroids may cause a reduction in growth velocity in pediatric patients [Children]. This effect has been observed in the absence of laboratory evidence of hypothalamic-pituitary-adrenal (HPA) axis suppression, suggesting that growth velocity is a more sensitive indicator of systemic corticosteroid exposure in pediatric patients than some commonly used tests of HPA axis function. The long-term effects of this reduction in growth velocity associated with intranasal corticosteroids, including the impact on final adult height, are unknown.
Adverse events (possible Side Effects) associated with controlled trials of Nasonex on humans 12 years of age and older include
- viral infection
- Epistaxis / Blood-Tinged Mucus
- Upper Respiratory Tract Infection
- Musculoskeletal Pain
In all of the above noticed effects EXCEPT for Vomiting the incidence for each were greater than the placebo (control) group.
Additional events that occurred in the Nasonex group at a rate greater than or equal to 2% of the studied group but less than 5% are:
arthralgia, asthma, bronchitis, chest pain, conjunctivitis, diarrhea, dyspepsia, earache, flu-like symptoms, myalgia, nausea, and rhinitis.
* This list is not exhaustive, there may be other problems involved with taking this medication. Ask your doctor and pharmacist about other possible side effects and any precautions you should be taking and any contraindications (reasons you should not take this drug)
Consult your doctor for advice, diagnosis and treatment.